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A
Essential Oils
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A1
Kehrl W, Sonnemann U, Dethlefsen U. Therapy for acute nonpurulent rhinosinusitis with cineole: results of a double-blind, randomized, placebo-controlled trial. Laryngoscope. 2004;114:738-742.
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A2
Tesche S, Metternich F, Sonnemann U, et al. The value of herbal medicines in the treatment of acute non-purulent rhinosinusitis: Results of a double-blind, randomised, controlled trial. Eur Arch Otorhinolaryngol. 2008 Apr 25.
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A3
Paul IM, Beiler JS, King TS, Clapp ER, Vallati J, Berlin CM. Vapor rub, petrolatum, and no treatment for children with nocturnal cough and cold symptoms. Pediatrics. 2010;126(6):1092-1099.
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B
Herbs
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B1
Coon JT, Ernst E. Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med. 2004;70:293-298.
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B2
Goel V, Lovlin R, Barton R, et al. Efficacy of a standardized echinacea preparation (EchinilinTM) for the treatment of the common cold: a randomized, double-blind, placebo-controlled trial. J Clin Pharm Ther. 2004;29:75-84.
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B3
Poolsup N, Suthisisang C, Prathanturarug S, Asawamekin A, Chanchareon U.
Andrographis paniculata in the symptomatic treatment of uncomplicated upper
respiratory tract infection: systematic review of randomized controlled trials. J Clin Pharm Ther. 2004 Feb;29(1):37-45.
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B4
O'Neil J, Hughes S, Lourie A, et al. Effects of echinacea on the frequency of upper respiratory tract symptoms: a randomized, double-blind, placebo-controlled trial. Ann Allergy Asthma Immunol. 2008;100:384-388.
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B5
Saena RC, Singh R, et al. A randomized double blind controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection. Phytomedicine. 2010 Mar;17(3-4):178-185.
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B6
Barrett B, Brown R, et al. Echinacea for treating the common cold: a randomized trial. Ann Intern Med. 2010 Dec 21;153(12):769-777.
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B7
Karsch-Völk M, Barrett B, et al. Echinacea for preventing and treating the common cold. Cochrane Databse Syst Rev. 2014 Feb 20;(2):CD000530.
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C
Supplements
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C1
Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey. Adv Ther.2001;18:189-93
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C2
Predy GN, Goel V, et al. Efficacy of an extract of North American ginseng containing poly-furanosyl-pyranosyl-saccharides for preventing upper respiratory tract infections: a randomized controlled trial. CMAJ. 2005 Oct 25;173(9):1043-1048.
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C3
Tubelius P, Stan V, Zachrisson A, et al. Increasing work-place healthiness with the probiotic Lactobacillus reuteri: A randomised, double-blind placebo-controlled study. Environ Health. 2005 Nov 7. [Epub ahead of print]
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C4
McElhaney JE, Goel V, et al. Efficacy of COLD-fx in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blinded, placebo-controlled trial. J Altern Complement Med. 2006 Mar;12(2):153-157.
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C5
Lizogub VG, Riley DS, Heger M. Efficacy of a pelargonium sidoides preparation in patients with the common cold: a randomized, double blind, placebo-controlled clinical trial. Explore (NY). 2007 Nov-Dec;3(6):573-84.
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C6
Prasad AS, Beck FW, Bao B, et al. Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. J Infect Dis. 2008 Feb 15.
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C7
Rautava S, Salminen S, Isolauri E. Specific probiotics in reducing the risk of acute infections in infancy—a randomised, double-blind, placebo-controlled study. Br J Nutr. 2008 Nov 6.
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C8
Cox AJ, Pyne DB, et al. Oral administration of the probiotic Lactobacillus fermentum VRI-003 and mucosal immunity in endurance athletes. Br J Sports Med. 2010 Mar;44(4):222-226.
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C9
Hemilä H. Zinc Lozenges may shorten the duration of colds: a systematic review. Open Respiratory Medicine Journal 2011;5:51‐58
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C10
Van Puyenbroeck K, Hens N, et al. Efficacy of daily intake of Lactobacillus casei Shirota on respiratory symptoms and influenza vaccination immune response: a randomized, double-blind, placebo-controlled trial in healthy elderly nursing home patients. Am J Clin Nutr. 2012 May;95(5):1165-1171.
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C11
Science M, Johnstone J, et al. Zinc for the treatment of the common cold: a systematic review and meta-analysis of randomized controlled trials. CMAJ. 2012 Jul 10;184(10):E551-E561.
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C12
Lee CS, Lee JH, et al. Preventive effect of Korean red ginseng for acute respiratory illness: a randomized and double-blind clinical trial. J Korean med Sci. 2012 Dec;27(12):1472-1478.
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C13
Singh M, DAS RR. Zinc for the common cold. Cochrane Database Syst Rev. 2013 Jun 18;(6):CD001364.
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C14
Hao Q, Dong BR, et al. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. 2015 Feb 3(2):CD006895.
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C15
Hemilä H, Chalker E. The effectiveness of high dose zinc acetate lozenges on various common cold symptoms: a meta-analysis. BMC family practice. 2015 Feb 25;16:24.
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D
Traditional Chinese Medicine
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D1
Wu T, Zhang J, Qiu Y, Xie L, Liu GJ. Chinese medicinal herbs for the common
cold. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD004782.
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D2
Wang C, Cao B, Liu QQ, et al. Oseltamivir compared with the Chinese Traditional Therapy maxingshigan-yinqiaosan in the treatment of H1N1 influenza: a randomized trial. Ann Intern Med. 2011;155(4):217-225.
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D3
Li G, Cai L, et al. Compound formulas of traditional Chinese medicine for the common cold: systematic review of randomized, placebo-controlled trials. Altern Ther Health med. 2015 Nov-Dec;21(6):48-57.
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E
Vitamins
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E1
Martineau AR, Jolliffe DA, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017 Feb 15;356:i6583.
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E2
Murdoch DR, Slow S, et al. Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial. JAMA. 2012 Oct 3;308(13):1333-1339.
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E3
Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev. 2013 Jan 31;(1):CD000980.
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E4
Ginde AA, Blatchford P, et al. High-dose monthly vitamin D for prevention of acute respiratory infection in older long-term care residents: a randomized clinical trial. J Am Geriatr Soc. 2017 Mar;65(3):496-503.